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replication cohort for rs12483205  (Thermo Fisher)


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    Structured Review

    Thermo Fisher replication cohort for rs12483205
    SNPs ( p <5×10 −5 ) associated with in vitro HIV-1 replication in monocyte-derived macrophages.
    Replication Cohort For Rs12483205, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/replication+cohort+for+rs12483205/pmc03045405-168-12-31?v=Thermo+Fisher
    Average 91 stars, based on 1 article reviews
    replication cohort for rs12483205 - by Bioz Stars, 2026-08
    91/100 stars

    Images

    1) Product Images from "Genome-Wide Association Study Identifies Single Nucleotide Polymorphism in DYRK1A Associated with Replication of HIV-1 in Monocyte-Derived Macrophages"

    Article Title: Genome-Wide Association Study Identifies Single Nucleotide Polymorphism in DYRK1A Associated with Replication of HIV-1 in Monocyte-Derived Macrophages

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0017190

    SNPs ( p <5×10 −5 ) associated with in vitro HIV-1 replication in monocyte-derived macrophages.
    Figure Legend Snippet: SNPs ( p <5×10 −5 ) associated with in vitro HIV-1 replication in monocyte-derived macrophages.

    Techniques Used: In Vitro

    The negative association between the rs12483205 minor allele and Gag p24 levels in MDM culture supernatant 14 days after inoculation with HIV-1, was found to match with the results from the genome-wide association study. Open circles represent results from donors with the CCR5 Δ32 wild-type genotype, filled circles from donors with the CCR5 wt/ Δ32 heterozygous genotype. MAJ, homozygous for the major allele; HZ, heterozygote; MIN, homozygous for the minor allele.
    Figure Legend Snippet: The negative association between the rs12483205 minor allele and Gag p24 levels in MDM culture supernatant 14 days after inoculation with HIV-1, was found to match with the results from the genome-wide association study. Open circles represent results from donors with the CCR5 Δ32 wild-type genotype, filled circles from donors with the CCR5 wt/ Δ32 heterozygous genotype. MAJ, homozygous for the major allele; HZ, heterozygote; MIN, homozygous for the minor allele.

    Techniques Used: GWAS

    Results ( p values) for association testing using the additive analysis model, between disease progression or viral load and the SNPs in DYRK1A , PDE8A , UBR7 , MOAP1 and SPOCK3 .
    Figure Legend Snippet: Results ( p values) for association testing using the additive analysis model, between disease progression or viral load and the SNPs in DYRK1A , PDE8A , UBR7 , MOAP1 and SPOCK3 .

    Techniques Used: Biomarker Discovery

    Untranslated regions (UTR) are shown as open blocks, whereas exons are shown as filled blocks. SNP rs12483205 lies in close proximity to a part of the 5′ UTR unique for splice variant 3.
    Figure Legend Snippet: Untranslated regions (UTR) are shown as open blocks, whereas exons are shown as filled blocks. SNP rs12483205 lies in close proximity to a part of the 5′ UTR unique for splice variant 3.

    Techniques Used: Variant Assay



    Similar Products

    replication cohort for rs12483205  (Thermo Fisher)
    91
    Thermo Fisher replication cohort for rs12483205
    SNPs ( p <5×10 −5 ) associated with in vitro HIV-1 replication in monocyte-derived macrophages.
    Replication Cohort For Rs12483205, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/replication+cohort+for+rs12483205/pmc03045405-168-12-31?v=Thermo+Fisher
    Average 91 stars, based on 1 article reviews
    replication cohort for rs12483205 - by Bioz Stars, 2026-08
    91/100 stars
    		  Buy from Supplier

    Image Search Results


    SNPs ( p <5×10 −5 ) associated with in vitro HIV-1 replication in monocyte-derived macrophages.

    Journal: PLoS ONE

    Article Title: Genome-Wide Association Study Identifies Single Nucleotide Polymorphism in DYRK1A Associated with Replication of HIV-1 in Monocyte-Derived Macrophages

    doi: 10.1371/journal.pone.0017190

    Figure Lengend Snippet: SNPs ( p <5×10 −5 ) associated with in vitro HIV-1 replication in monocyte-derived macrophages.

    Article Snippet: ABI TaqMan® SNP genotyping assays were used to genotype DNA from the replication cohort for rs12483205 (C_31609775_10), rs12909130 (C_1342209_10) as a proxy for rs2304418, rs2905 (C_3236245_20), rs1046099 (C_7585751_10) and rs17519417 (C_33238869_10) (Applied Biosystems, Carlsbad, CA, USA).

    Techniques: In Vitro

    The negative association between the rs12483205 minor allele and Gag p24 levels in MDM culture supernatant 14 days after inoculation with HIV-1, was found to match with the results from the genome-wide association study. Open circles represent results from donors with the CCR5 Δ32 wild-type genotype, filled circles from donors with the CCR5 wt/ Δ32 heterozygous genotype. MAJ, homozygous for the major allele; HZ, heterozygote; MIN, homozygous for the minor allele.

    Journal: PLoS ONE

    Article Title: Genome-Wide Association Study Identifies Single Nucleotide Polymorphism in DYRK1A Associated with Replication of HIV-1 in Monocyte-Derived Macrophages

    doi: 10.1371/journal.pone.0017190

    Figure Lengend Snippet: The negative association between the rs12483205 minor allele and Gag p24 levels in MDM culture supernatant 14 days after inoculation with HIV-1, was found to match with the results from the genome-wide association study. Open circles represent results from donors with the CCR5 Δ32 wild-type genotype, filled circles from donors with the CCR5 wt/ Δ32 heterozygous genotype. MAJ, homozygous for the major allele; HZ, heterozygote; MIN, homozygous for the minor allele.

    Article Snippet: ABI TaqMan® SNP genotyping assays were used to genotype DNA from the replication cohort for rs12483205 (C_31609775_10), rs12909130 (C_1342209_10) as a proxy for rs2304418, rs2905 (C_3236245_20), rs1046099 (C_7585751_10) and rs17519417 (C_33238869_10) (Applied Biosystems, Carlsbad, CA, USA).

    Techniques: GWAS

    Results ( p values) for association testing using the additive analysis model, between disease progression or viral load and the SNPs in DYRK1A , PDE8A , UBR7 , MOAP1 and SPOCK3 .

    Journal: PLoS ONE

    Article Title: Genome-Wide Association Study Identifies Single Nucleotide Polymorphism in DYRK1A Associated with Replication of HIV-1 in Monocyte-Derived Macrophages

    doi: 10.1371/journal.pone.0017190

    Figure Lengend Snippet: Results ( p values) for association testing using the additive analysis model, between disease progression or viral load and the SNPs in DYRK1A , PDE8A , UBR7 , MOAP1 and SPOCK3 .

    Article Snippet: ABI TaqMan® SNP genotyping assays were used to genotype DNA from the replication cohort for rs12483205 (C_31609775_10), rs12909130 (C_1342209_10) as a proxy for rs2304418, rs2905 (C_3236245_20), rs1046099 (C_7585751_10) and rs17519417 (C_33238869_10) (Applied Biosystems, Carlsbad, CA, USA).

    Techniques: Biomarker Discovery

    Untranslated regions (UTR) are shown as open blocks, whereas exons are shown as filled blocks. SNP rs12483205 lies in close proximity to a part of the 5′ UTR unique for splice variant 3.

    Journal: PLoS ONE

    Article Title: Genome-Wide Association Study Identifies Single Nucleotide Polymorphism in DYRK1A Associated with Replication of HIV-1 in Monocyte-Derived Macrophages

    doi: 10.1371/journal.pone.0017190

    Figure Lengend Snippet: Untranslated regions (UTR) are shown as open blocks, whereas exons are shown as filled blocks. SNP rs12483205 lies in close proximity to a part of the 5′ UTR unique for splice variant 3.

    Article Snippet: ABI TaqMan® SNP genotyping assays were used to genotype DNA from the replication cohort for rs12483205 (C_31609775_10), rs12909130 (C_1342209_10) as a proxy for rs2304418, rs2905 (C_3236245_20), rs1046099 (C_7585751_10) and rs17519417 (C_33238869_10) (Applied Biosystems, Carlsbad, CA, USA).

    Techniques: Variant Assay